 | Arnold Schwarzenegger als Major Alan "Dutch" Schaefer |
 | Carl Weathers als Al Dillon |
 | Elpidia Carrillo als Anna Gonsalves |
 | Jesse Ventura als Blain Cooper |
 | Sonny Landham als Billy Sole |
 | Bill Duke als Mac Eliot |
 | Richard Chaves als Jorge "Poncho" Ramirez |
 | R. G. Armstrong als Major General Homer Phillips |
 | Shane Black als Rick Hawkins |
 | Kevin Peter Hall als Predator / Helicopter Pilot |
 | Steve Boyum als Hostage Executed by the Russian (uncredited) |
 | William H. Burton Jr. als Guerilla Soldier Shot Down from Tree (uncredited) |
 | Henry Kingi als Guerilla Soldier Blown Up in Van (uncredited) |
 | Peter Cullen als Predator (voice) (uncredited) |
 | Sven-Ole Thorsen als Russian Officer (uncredited) |
 | Jack Verbois als Guerilla Soldier Helicopter Pilot (uncredited) |
 | Franco Columbu als Medic (uncredited) |
| John McTiernan | Director |
| Joel Silver | Producer |
| Lawrence Gordon | Producer |
| Jim Thomas | Author |
| John Thomas | Author |
| Donald McAlpine | Director of Photography |
| Alan Silvestri | Original Music Composer |
| John Vallone | Production Design |
| Jackie Burch | Casting |
| Mark Helfrich | Editor |
| John F. Link | Editor |
| Marilyn Vance | Costume Design |
| Frank Richwood | Art Direction |
| Jorge Sainz | Art Direction |
| Enrique Estévez | Set Decoration |
| Bertha Chiu | Hairstylist |
| Scott H. Eddo | Makeup Designer |
| Carlos Horcasitas | Hairstylist |
| Beau Marks | First Assistant Director |
| Henry Alvarez | Sculptor |
| Marc Fambro | Carpenter |
| Antonio Mata | Property Master |
| Frank Mitchell | Greensman |
| Salvador Pena | Construction Coordinator |
| Francisco Ramirez | Greensman |
| Macedonio Ramos | Set Dresser |
| Tommy Tomlinson | Property Master |
| George H. Anderson | Supervising Dialogue Editor |
| Richard L. Anderson | Supervising Sound Effects Editor |
| Gene Corso | Sound Effects Editor |
| Cindy Marty | Dialogue Editor |
| Steve Richardson | Foley Editor |
| Hank Salerno | ADR Editor |
| Corinne Sessarego | ADR Editor |
| Catherine Shorr | Sound Effects Editor |
| Richard Shorr | Sound Effects Editor |
| David E. Stone | Supervising Sound Effects Editor |
| Bill Voigtlander | ADR Editor |
| Gary Wright | Sound Effects Editor |
| Laurencio Cordero | Special Effects Supervisor |
| Al Di Sarro | Special Effects Supervisor |
| Michael Bigelow | Visual Effects Supervisor |
| Robert M. Greenberg | Visual Effects Producer |
| Joel Hynek | Visual Effects Supervisor |
| J.W. Kompare | Visual Effects Editor |
| Robert Mrozowski | Animation Supervisor |
| Craig R. Baxley | Stunt Coordinator |
| Fernando Calvillo | Gaffer |
| Juan Iniestra | Key Grip |
| Grahame Litchfield | Key Grip |
| Warren Mearns | Gaffer |
| Patrick Nash | Key Grip |
| Zade Rosenthal | Still Photographer |
| Alfredo Ruvalcaba | Still Photographer |
| Robert B. Harris | Costume Supervisor |
| James W. Tyson | Costume Supervisor |
| James B. Campbell | Orchestrator |
| Michael Tronick | Music Editor |
| Alejandro Madrid Bonilla | Pilot |
| Gabriela Gurrola | Script Supervisor |
| Peter McKernan | Pilot |
| Charles A. Tamburro | Aerial Coordinator |
| Michael Tamburro | Pilot |
| Marion Tumen | Script Supervisor |
| Bobby Bass | Stunts |
| Gary Baxley | Stunts |
| Steve Boyum | Stunts |
| Jophery C. Brown | Stunts |
| Tony Brubaker | Stunts |
| Steven Chambers | Stunts |
| Doug Coleman | Stunts |
| Leon Delaney | Stunts |
| David Drazes | Stunts |
| David Efron | Stunts |
| Robert Hammond | Stunts |
| Norman Howell | Stunts |
| Richard Humphreys | Stunts |
| Sergio Kato | Stunts |
| Peter Kent | Stunts |
| Henry Kingi | Stunts |
| Joel Kramer | Stunts |
| Jack Verbois | Stunts |
| Monty Jordan | Stunts |
| Eddie L. Watkins | Stunts |
| Beau Marks | Associate Producer |
| John Vallone | Associate Producer |
| Laurence Pereira | Executive Producer |
| Jim Thomas | Executive Producer |
| John Davis | Producer |
| Theresa Wachter | Assistant Art Director |
| Frank Bryson | Camera Operator |
| Robert Agganis | First Assistant Camera |
| Robert Agganis | Steadicam Operator |
| Manuel Paredes Murillo | Driver |
| Margarito Fuentes Gutiérrez | Transportation Co-Captain |
| Charles Enzen | Transportation Coordinator |
| Dale E. Grahn | Color Timer |
| Adolfo Lara | Best Boy Electric |
| Patti Calhoun | Production Coordinator |
| Beau Marks | Production Manager |
| Jorge Gómez | Boom Operator |
| Dennis S. Sands | Scoring Mixer |
| Manuel Topete | Sound Mixer |
| Donald Meyers | Storyboard |
| John Pospisil | Special Sound Effects |
| David W. Gray | Dolby Consultant |
| Anna Roth | Unit Manager |
| J. Tom Archuleta | Second Assistant Director |
| Craig R. Baxley | Second Unit Director |
| Benito Cano | Assistant Property Master |
| Kevin E. Carpenter | ADR Mixer |
| Vic Zaslav | ADR Recordist |
| Vanessa Theme Ament | Foley Artist |
| J.R. Westen | Foley Mixer |
| Steve Slocomb | Visual Effects Camera |
| Gregory J. Barnett | Stunt Double |
| Guillermo Moysen | Assistant Camera |
| Antonio Ramírez 'Puma' | Dolly Grip |
| Billy DaMota | Casting Assistant |
| Jack Hooper | Negative Cutter |
| Alan Silvestri | Conductor |
| Humberto Gurza | Animal Wrangler |
| Guillermo Castillo | Extras Casting |
| Guillermo 'Memo' Carreño | Production Assistant |
| Gary Goldman | Technical Advisor |
| William Stout | Creature Design |
| Nikita Knatz | Production Illustrator |
| John Oteri | Camera Operator |
| Screaming Mad George | Special Effects Makeup Artist |
| Tony Holtham | Gaffer |
| William H. Burton Sr. | Stunts |
| Jean-Claude Van Damme | Stunts |
| Jeff Dawn | Makeup Artist |
| Laurencio Cordero | Special Effects |
