 | Michael Moriarty als David 'Mo' Rutherford |
 | Andrea Marcovicci als Nicole Kendall |
 | Garrett Morris als 'Chocolate Chip' Charlie W. Hobbs |
 | Paul Sorvino als Colonel Malcolm Grommett Spears |
 | Scott Bloom als Jason |
 | Danny Aiello als Vickers |
 | Patrick O'Neal als Fletcher |
 | James Dixon als Postman |
 | Alexander Scourby als Evans |
 | Russell Nype als Richards |
| Gene O'Neill als Scientist |
| Catherine Schultz als Waitress |
| James Dukas als Gas Attendant |
| Peter Hock als Miner |
 | Brian Bloom als Jason's Brother |
| Ann Dane als Hostess |
 | Rutanya Alda als Psychologist |
 | Adrianne Sachs als Studio Aide |
| Nicolas De Toth als Griswald |
 | Brooke Adams als Stuff Commercial Spokeswoman |
 | Laurene Landon als Stuff Commercial Spokeswoman |
 | Tammy Grimes als Stuff Commercial Spokeswoman |
 | Abe Vigoda als Stuff Commercial Spokesman |
| Clara Peller als Stuff Commercial Spokeswoman |
 | Eric Bogosian als Supermarket Clerk (uncredited) |
| Brad Rijn als Supermarket Clerk (uncredited) |
 | Patrick Dempsey als Underground Stuff Buyer (uncredited) |
 | Mira Sorvino als Factory Worker (uncredited) |
 | John Newton als Howard |
| Robert Frank Telfer als Jason's father |
| Colette Blonigan als Jason's mother |
| Heidi Miller als Girl in Franchise |
| Larry Cohen | Director |
| Larry Cohen | Writer |
| Jim Danforth | Visual Effects |
| Paul Kurta | Producer |
| Armond Lebowitz | Editor |
| Timothy D'Arcy | Costume Design |
| Ed French | Makeup Effects |
| Rick Stratton | Makeup Effects |
| Larry Cohen | Executive Producer |
| Bret Culpepper | Special Effects |
| Anthony Guefen | Original Music Composer |
| Paul Glickman | Director of Photography |
| Marleen Marta | Art Direction |
| John Lambert | Visual Effects |
| Michael Maddi | Makeup Effects |
| Steve Neill | Makeup Effects |
| Paul Gentry | Visual Effects |
| David Allen | Visual Effects |
| David Stipes | Visual Effects |
| George Stoll | Art Direction |
| Jim Doyle | Visual Effects |
| Arnold Finkelstein | Assistant Sound Editor |
| Peter Friedman | Production Assistant |
| Daniel Lupi | Production Assistant |
| James Dixon | Production Supervisor |
| Mike Dooley | Grip |
| Barbara Zitwer | Location Scout |
| Dwight Dixon | Additional Music |
| Jill S. Cohen | Production Assistant |
| Cecilia Kate Roque | Production Coordinator |
| Craig Lyman | Special Effects Makeup Artist |
| Mark Croll | Unit Production Manager |
| Harvey Waldman | First Assistant Director |
| Ted Rae | Modeling |
| Richard Benenson | Intern |
| Ian Clark | Title Designer |
| Heidi Shulman | Costume Supervisor |
| John Penney | Additional Editor |
| Jane Goldenberg | Intern |
| Ken Howard | Still Photographer |
| Kathryn Conners | Extras Casting |
| Armond Lebowitz | Music Editor |
| Elana Golden | Script Supervisor |
| Drew Dillard | Production Assistant |
| Debra Fernandez | Choreographer |
| Richard Seaman | Music Producer |
| Jenny Fitzgibbons | Second Assistant Director |
| Joanna Jimenez | Assistant Sound Editor |
| Scott Buckler | Electrician |
| Cindy Lagerstrom | Grip |
| Pamela Wagener | Production Assistant |
| Jim Danforth | Matte Painter |
| J. Christian Ingvordsen | Key Grip |
| Timothy John | Costume Designer |
| Bob Schnur | Location Scout |
| Athan Gigakos | Sound Re-Recording Mixer |
| Rolf Pardula | Sound Mixer |
| Darryl Green | Gaffer |
| Joe Violante | Technical Advisor |
| Nelson Elwell | Grip |
| Robert A. Preston | Grip |
| Rosanne Lebowitz | Assistant Editor |
| Eamonn Bowles | Production Assistant |
| Meredith Zamsky | Production Assistant |
| Harvey Livingston Jr. | Hair Designer |
| Harvey Livingston Jr. | Makeup Artist |
| Steven Kaman | Electrician |
| Steven Felder | Production Consultant |
| Barry Shils | Associate Producer |
| Matthew Corey | Production Assistant |
| Ira Halberstadt | Production Manager |
| Billy Byrne | Apprentice Sound Editor |
| Stuart Deutsch | Boom Operator |
| Eugene Gearty | Sound Effects Editor |
| Lisa Wytrval | Apprentice Sound Editor |
| Mark Sullivan | Matte Painter |
| Jery Hewitt | Stunt Coordinator |
| Philippe Carr-Forster | First Assistant Camera |
| Frederick Iannone | First Assistant Camera |
| Melissa Cohen | Production Assistant |
| Kim Robinson | Assistant Makeup Artist |
| Charles Weaver | Props |
| Val Kuklowsky | Supervising Sound Editor |
| Cathy Anderson | Location Scout |
| Harry Walton | Matte Painter |
| Mark Croll | First Assistant Director |
| Jim Danforth | Second Unit Director |
| Val DeSalvo | Electrician |
| Gail Warren | Second Assistant Camera |
| Larry Justice | Swing |
