 | Charlize Theron als Andromache of Scythia / Andy |
 | KiKi Layne als Nile Freeman |
 | Matthias Schoenaerts als Sebastien Le Livre / Booker |
 | Marwan Kenzari als Yusuf Al-Kaysani / Joe |
 | Luca Marinelli als Nicolò di Genova / Nicky |
 | Veronica Ngo als Quynh |
 | Chiwetel Ejiofor als Copley |
 | Uma Thurman |
 | Henry Golding |
| Victoria Mahoney | Director |
| Greg Rucka | Graphic Novel |
| Gina Prince-Bythewood | Producer |
| Greg Rucka | Screenplay |
| Greg Rucka | Executive Producer |
| David Ellison | Producer |
| Dana Goldberg | Producer |
| Don Granger | Producer |
| Charlize Theron | Producer |
| Beth Kono | Producer |
| A.J. Dix | Producer |
| Marc D. Evans | Producer |
| Leandro Fernandez | Graphic Novel Illustrator |
| Rob Fournier | Supervising Armorer |
| Denis L. Stewart | Unit Production Manager |
| Marco Cardilli | Assistant Art Director |
| Cristiano Donzelli | Storyboard Artist |
| Scott Bunce | First Assistant Director |
| Briseide Siciliano | Art Direction |
| Marco Furbatto | Art Direction |
| Luca Waldman | Assistant Production Manager |
| Kelly Clear | Chief Lighting Technician |
| Craig Anthony | Set Costumer |
| John Naclerio | Unit Production Manager |
| Diego Avolio | Key Makeup Artist |
| Gabriele Gregorini | Key Hair Stylist |
| Jacenda Burkett | Makeup Artist |
| Flavio Meloni | Lighting Programmer |
| Eli Joshua Adé | Still Photographer |
| Cid Swank | Unit Publicist |
| Denis L. Stewart | Executive Producer |
| Aurélia Agel | Stunt Double |
| Gosia Zur | Second Unit Director of Photography |
| Cristiano Sergioli | Techno Crane Operator |
| Mary E. Vogt | Costume Designer |
| Chiara Cocchi | Video Assist Operator |
| Barry Ackroyd | Director of Photography |
| Ruth Barrett | Original Music Composer |
| Dan Bradley | Second Unit Director |
| Lauren Mary Kim | Stunt Double |
